Thomas E. Schlaepfer, MD

Magnetic Seizure Therapy (MST) refers to the intentional induction of a seizure under anesthesia and muscle relaxation for therapeutic purposes using repetitive transcranial magnetic stimulation (rTMS)

Principle of Seizure Induction

Effects of MST and ECT; data from:

Kayser S, Bewernick B, Grubert C, Hadrysiewicz B, Axmacher N, Schlaepfer TE (2010): Antidepressant effects, of magnetic seizure therapy and electroconvulsive therapy, in treatment-resistant depression. Journal of Psychiatric Research [Epub ahead of print].
PMID: 20951997

Currently we have the following MST studies registered with Clinicaltrials.gov:

NCT00770783 Magnetic Seizure Therapy (MST) for Treatment Resistant Major Depression
NCT01318018 Investigation on the Value of Bilateral Index (BIS) Monitoring for Magnetic Seizure Versus Electroconvulsive Therapy