Neurobiology of Psychiatric Disorders, Volume 106: Handbook of Clinical Neurology
Thomas E Schlaepfer (Editor), Charles B. Nemeroff MD PhD (Editor)

This new volume in the Handbook of Clinical Neurology presents a comprehensive review of the fundamental science and clinical treatment of psychiatric disorders. Advances in neuroscience have allowed for dramatic advances in the understanding of psychiatric disorders and treatment. Brain disorders, such as depression and schizophrenia, are the leading cause of disability worldwide. It is estimated that over 25% of the adult population in North America are diagnosed yearly with at least one mental disorder and similar results hold for Europe. Now that neurology and psychiatry agree that all mental disorders are in fact, "brain diseases," this volume provides a foundational introduction to the science defining these disorders and details best practices for psychiatric treatment.

ISBN-10: 0444520023 | ISBN-13: 978-0444520029
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Deep Brain Stimulation: A New Frontier in Psychiatry
Chapter 9: Deep Brain Stimulation of the Human Reward System as a Putative Treatment for Refractory Major Depression
T. E. Schlaepfer, V. A. Coenen and B. H. Bewernick

Deep Brain Stimulation: A New Frontier in Psychiatry provides an overview of current developments and the future possibilities of deep brain stimulation for patients with therapy-refractory psychiatric disorders. The side-by-side presentation of clinical applications and animal research provides a truly translational approach. Also included is a special chapter on the ethical issues involved in deep brain stimulation in psychiatry. Deep brain stimulation of selected brain areas has been shown to result in a substantial improvement of symptoms and quality of life in patients suffering from obsessive-compulsive disorder, major depressive disorder and drug addiction. Although it is still an experimental therapy and the number of psychiatric patients that are treated is low, its effectiveness and safety makes deep brain stimulation the most promising therapy for treating other serious and life-threatening psychiatric conditions.

ISBN-10: 3642309909 ISBN-13: 978-3642309908
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Deep brain stimulation: Method, Indications, Locations and Efficacy In: Swartz C editor. Electroconvulsive Therapy and Neuromodulation. Cambridge, MA: Cambridge University Press.
Schlaepfer TE, Bewernick BH (2009):

ISBN-13: 9780521883887

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Angst und Depression
Prof. Dr. Thomas Schläpfer und Dipl.-Psych. Caroline Frick
Klinik und Poliklinik für Psychiatrie und Psychotherapie, Universitätsklinikum Bonn
UNI-MED Science, 1. Auflage 2007, 76 Seiten, 9 Abb., Hardcover,
ISBN 978-3-89599-256-8

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Deep Brain Stimulation for Depression in McGraw-Hill Yearbook of Science & Technology 2007. New York, NY: McGraw-Hill
Schlaepfer TE

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Bipolare Störungen in Therapie psychischer Erkrankungen 2006/ 2007 State of the Art München, Deutschland: Elsevier Urban & Fischer.
Schläpfer TE, Greil W

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Repetitive transcranial magnetic stimulation (rTMS) in depression. Poiesis & Praxis. 2006;4(2):111-127.
Schlaepfer TE, Kosel M, Fisch HU.

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